If the genetic material formed from the parents is injected into a healthy egg from a anonymous donor with normal mitochondria what is the role of donor from the point of law?
Though the genes are most important to cause diseases, it is also the composition, the team play of the genes that prevents diseases. Not only the genes but also the level of the gene function is important. The currency of cell is ATP, if we play a gene to change ATP currency in cell, no matter the gene is there or not, we may change the phenotype of cell function. At present scientific world, we are at a good level in molecular, genetic science; but, not a level of precisely arranging the ATP currency in cell. Such random arbitrary intervention is only a trial without any guarantee for definite solution because of ATP limitation in cell.
Yes, from the point of the law, the baby has three or more parents.
Even an animal mitochondria will make better or worse the human gene composition. Adding one missing gene might waste some energy currencies of cell to block very important paths, intracellular substrate levels.
Even an animal donor by the Law should be called parent for being able to block some paths to cause or alleviate a disease. Only few extraordinary genes that regulates brain electrical circuits, ion transport, some oxygenated fat synthesis etc are higher to animals, as I always said, when investigated, the gene superiority of human creature to animals is not that much; and, explanation is knocking down some animal characteristics. Then comes the ideal human decription? Should we fly a bird do, swim as a fish do, use our brain as a computer storage do, hear as some animals do; stay warm as animals do in winter; human cell is not a waste bin to add and add all the genes, there are superior characteristics of the human, not having too much genes that waste important energy sources without any impact on human creature's superior characteristics, is also superiority method. The cost of a gene addition important. The cell size, cell doubling energy level should not wasted.
A tailor should not waste all the fabrics on unimportant things; then no available fabric to important places.
Tube babies are methods of helping natural events, but playing with mitochondria is not at all a natural event.
